Intended Use
Acceptable panel to detect the two most common inherited thrombophilias: factor V Leiden related (R506Q variant of the F5 gene) and prothrombin related (G20210A variant of the F2 gene). This panel also detects thrombophilia associated with pathogenic variants in the MTHFR gene (c.665C>T).
Specimen Required
Lavender (EDTA), Pink (K2EDTA), FFPE
Patient Preparation
- Sample Collection: 2 Tubes / EDTA Blood / 2 mL per tube or FFPE
- Specimen Preparation: Do not freeze. Transport 3 mL whole blood. (Min: 1 mL)
- Storage/Transport Temperature: Refrigerated
- Unacceptable Conditions
- Plasma or serum.
- Heparinized specimens.
- Frozen specimens in glass collection tubes.
- Remarks: –
- Stability: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month.
Methodology
The test qualitatively detects mutations for Factor II, Factor V Leiden, and MTHFR using allelic discrimination real-time PCR assay.
Sample Received to Report Turnaround Time (TAT)
Twice in a week (Scheduled Test)
Reference Interval
–
Interpretive Data
Refer to the Report
Resources
- Additional Technical Information
- Test Request Form
Sample Reports
- Enhanced Report
- See report